Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice. EC number: CAS number: The test item was applied once to 5 dose-groups of rats 5 male and 5 female Wistar rats per dose-group in doses of 3. The observation period was 14 days. At the highest dose Clinical signs were reddening of stomach and intestinal mucosa in dead animals.
A loss of hair at perineum was observed among the survivors at the end of the study. Subsequently the surviving animals showed normal behaviour again throughout the observation period.
Therefore under the conditions of this study the acute toxicity of 3-Isocyanatomethyl Information on Registered Substances comes from registration dossiers which have been assigned a registration number. This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice. Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner s of the respective information might violate the rights of the owner.
REACH 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Substance Identity Administrative Information. Ecotoxicological Summary Aquatic toxicity Endpoint summary Short-term toxicity to fish Long-term toxicity to fish Short-term toxicity to aquatic invertebrates Long-term toxicity to aquatic invertebrates Toxicity to aquatic algae and cyanobacteria Toxicity to aquatic plants other than algae Toxicity to microorganisms Endocrine disrupter testing in aquatic vertebrates β in vivo Toxicity to other aquatic organisms Sediment toxicity Terrestrial toxicity Endpoint summary Toxicity to soil macroorganisms except arthropods Toxicity to terrestrial arthropods Toxicity to terrestrial plants Toxicity to soil microorganisms Toxicity to birds Toxicity to other above-ground organisms Biological effects monitoring Biotransformation and kinetics Additional ecotoxological information.
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